Anti-HNRNPC (C-term) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	P07910
Gene Id	3183
Gene Symbols	HNRNPC
Protein Name / Synonyms	HNRNPC (C-term)
Clonality	Polyclonal
Preparation	This HNRNPC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 279-306 amino acids from the C-terminal region of human HNRNPC.
Concentration (lot specific)	0.4 mg/ml
Recommended Applications	IHC-P, Western Blotting
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene can act as a tetramer and is involved in the assembly of 40S hnRNP particles. Multiple transcript variants encoding at least two different isoforms have been described for this gene. [provided by RefSeq].

Specificity

Predicted Reactivity

Mouse, Rabbit

Other Names

HNRNPC; HNRPC; Heterogeneous nuclear ribonucleoproteins C1/C2

NCBI Accession #

NP_001070910.1;NP_001070911.1;NP_004491.2;NP_112604.2

Other Accession #

O77768; Q9Z204; NP_004491.2

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

33670

Recommended Dilutions

IHC: 1:50-100; WB: 1:1000

	HNRNPC antibody (C-term) (Cat# 102-10775) immunohistochemistry analysis in formalin fixed and paraffin embedded human bladder carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the HNRNPC antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
	HNRNPC Antibody (C-term) (Cat# 102-10775) western blot analysis in Jurkat,K562,U251 cell line lysates (35ug/lane).This demonstrates the HNRNPC antibody detected the HNRNPC protein (arrow).

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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