Anti-HOXB8 (C-term) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	P17481
Gene Id	3218
Gene Symbols	HOXB8
Protein Name / Synonyms	HOXB8 (C-term)
Clonality	Polyclonal
Preparation	This HOXB8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 215-243 amino acids from the C-terminal region of human HOXB8.
Concentration (lot specific)	0.5 mg/ml
Recommended Applications	Western Blotting
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

This gene is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in development. Increased expression of this gene is associated with colorectal cancer. Mice that have had the murine ortholog of this gene knocked out exhibit an excessive pathologic grooming behavior. This behavior is similar to the behavior of humans suffering from the obsessive-compulsive spectrum disorder trichotillomania.

Specificity

Other Names

HOXB8; HOX2D; Homeobox protein Hox-B8; Homeobox protein Hox-2.4; Homeobox protein Hox-2D

NCBI Accession #

NP_076921.1

Other Accession #

NP_076921.1

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

27574

Recommended Dilutions

WB: 1:1000

HOXB8 Antibody (C-term) (Cat# 102-12879) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the HOXB8 antibody detected the HOXB8 protein (arrow).

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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