RayBiotech

3607 Parkway Ln Ste 200 Norcross, Georgia 30092

www.RayBiotech.com | info@raybiotech.com

770-729-2992 | +1-888-494-8555

ISO 13485:2016 cGMP

Anti-HRD1 (N-term) Antibody

Catalog #: 102-15014

Rabbit Anti-Human HRD1 (N-term) Antibody, 400 ul

Product Description

Specifications

Size400 µL
Estimated Lead Time1-2 weeks
SpeciesHuman
Host SpeciesRabbit
Accession Number
Q86TM6
Gene Id
84447
Gene Symbols
SYVN1
Protein Name / Synonyms
HRD1 (N-term)
ClonalityPolyclonal
PreparationThis HRD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 106-138 amino acids from the N-terminal region of human HRD1.
Concentration (lot specific)
2.0 mg/ml
Recommended ApplicationsWestern Blotting
Shipping TypeBlue ice
Storage-20°C

Description

Introduction

HRD1 encodes a protein involved in endoplasmic reticulum (ER)-associated degradation. The encoded protein removes unfolded proteins, accumulated during ER stress, by retrograde transport to the cytosol from the ER. This protein also uses the ubiquitin-proteasome system for additional degradation of unfolded proteins. This gene and the mitochondrial ribosomal protein L49 gene use in their respective 3' UTRs some of the same genomic sequence.

Specificity

Predicted Reactivity
Mouse, Xenopus
Other Names
SYVN1; HRD1; KIAA1810; E3 ubiquitin-protein ligase synoviolin; Synovial apoptosis inhibitor 1
NCBI Accession #
NP_115807.1;NP_757385.1
Other Accession #
Q5XHH7; Q6NRL6; Q9DBY1

Format

Type
Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
67685
Recommended Dilutions
WB: 1:1000
Western blot analysis of HRD1 Antibody (N-term) (Cat# 102-15014) in SK-BR-3 cell line lysates (35ug/lane). HRD1 (arrow) was detected using the purified Pab.

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.