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Anti-HSD17B4 (Center) Antibody
Catalog #: 102-11605
Rabbit Anti-Human HSD17B4 (Center) Antibody, 400 ul
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | P51659 |
| Gene Id | 3295 |
| Gene Symbols | HSD17B4 |
| Protein Name / Synonyms | HSD17B4 (Center) |
| Clonality | Polyclonal |
| Preparation | This HSD17B4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 341-370 amino acids from the Central region of human HSD17B4. |
| Concentration (lot specific) | 0.250 mg/ml |
| Recommended Applications | Western Blotting, IHC-P |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
The protein encoded by this gene is a bifunctional enzyme that is involved in the peroxisomal beta-oxidation pathway for fatty acids. It also acts as a catalyst for the formation of 3-ketoacyl-CoA intermediates from both straight-chain and 2-methyl-branched-chain fatty acids. Defects in this gene that affect the peroxisomal fatty acid beta-oxidation activity are a cause of D-bifunctional protein deficiency (DBPD). An apparent pseudogene of this gene is present on chromosome 8. [provided by RefSeq].
Specificity
Other Names
HSD17B4; EDH17B4; Peroxisomal multifunctional enzyme type 2; 17-beta-hydroxysteroid dehydrogenase 4; D-bifunctional protein; Multifunctional protein 2; (3R)-hydroxyacyl-CoA dehydrogenase; Enoyl-CoA hydratase 2; 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholest-24-enoyl-CoA hydratase
NCBI Accession #
NP_000405.1;NP_001186220.1;NP_001186221.1
Other Accession #
NP_000405.1
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
79686
Recommended Dilutions
WB: 1:1000; IHC: 1:10-50
 | HSD17B4 Antibody (Center) (Cat# 102-11605) western blot analysis in MCF-7,ZR-75-1,HepG2 cell line lysates (35ug/lane).This demonstrates the HSD17B4 antibody detected the HSD17B4 protein (arrow). |
 | HSD17B4 Antibody (Center) (Cat# 102-11605)immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of HSD17B4 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.