Anti-HSPBP1 (N-term) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	Q9NZL4
Gene Id	23640
Gene Symbols	HSPBP1
Protein Name / Synonyms	HSPBP1 (N-term)
Clonality	Polyclonal
Preparation	This HSPBP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 69-97 amino acids from the N-terminal region of human HSPBP1.
Concentration (lot specific)	0.5 mg/ml
Recommended Applications	Western Blotting, IHC-P
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

HSPBP1 inhibits HSPA1A chaperone activity by changing the conformation of the ATP-binding domain of HSPA1A and interfering with ATP binding. Interferes with ubiquitination mediated by STUB1 and inhibits chaperone-assisted degradation of immature CFTR.

Specificity

Predicted Reactivity

Mouse, Rat, Monkey

Other Names

HSPBP1; HSPBP; Hsp70-binding protein 1; Heat shock protein-binding protein 1; Hsp70-binding protein 2; Hsp70-interacting protein 1; Hsp70-interacting protein 2

NCBI Accession #

NP_001123578.1;NP_036399.3

Other Accession #

Q6IMX7; Q99P31; Q4R588; NP_036399.3; NP_001123578.1

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

39474

Recommended Dilutions

WB: 1:1000; IHC: 1:10-50

	HSPBP1 Antibody (N-term) (Cat# 102-12647) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the HSPBP1 antibody detected the HSPBP1 protein (arrow).
	HSPBP1 Antibody (N-term) (102-12647)immunohistochemistry analysis in formalin fixed and paraffin embedded human heart tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of HSPBP1 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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