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Anti-Human beta-2-microglobulin (B2M) Antibody, Purified
Catalog #: 136-00049
Human beta-2-microglobulin Antibody, monoclonal Mouse . Validated for flow cytometry.
Product Description
Specifications
| Size | 100 µg, 500 µg |
| Estimated Lead Time | 1-2 business days |
| Species | Human |
| Host Species | Mouse |
| Protein Name / Synonyms | β2M |
| Clonality | Monoclonal |
| Preparation | The antibody was purified by affinity chromatography. |
| Format | Lyophilized |
| Concentration (lot specific) | Lyophilized |
| Buffers | PBS, pH 7.2-7.4; Carrier-free |
| Recommended Applications | Flow Cytometry |
| Reconstitution | Reconstitute in desired amount of PBS. |
| Research Area | Cardiovascular Disease |
| Shipping Type | Ambient temperature |
| Storage | -20°C |
Description
Product Features
- Serum-free media used for cell culture of hybridomas to minimize bovine antibody contamination
- Gentle elution at pH 4.0 to minimize antibody degradation
- Protein A, G & L affinity purification
- High purity
- Carrier free
- Endotoxin-free
Description
β2M is a non polymorphic protein with an Ig-like domain. It serves as the light chain in MHC Class I molecules, and is accociated with all classical MHC class I heavy chains. As with MHC class I, β2M is expressed on all nucleated cells except for neurons. β2M tends to be overexpressed in multiple myeloma and lymphoma, as well as in several other types of cancers, so it can be used as a marker for these diseases.
Recommended Usage
Each lot of antibody has been tested by flow cytometry staining. We suggest use ≤ 0.5 µg per million cells in 100 µl volume of staining buffer. Researchers are recommended to further titrate this antibody at the optimal concentration for each specific application.
Storage / Stability
Keep the lyophilized antibodies at -20 °C. Once reconstituted with PBS, store at 2 °C - 8 °C for less than 3 weeks or freeze at -20°C for long term storage. Please limit freeze and thaw cycles.