3607 Parkway Ln Ste 200 Norcross, Georgia 30092
www.RayBiotech.com | info@raybiotech.com
770-729-2992 | +1-888-494-8555
ISO 13485:2016 cGMP
Anti-Human CD279 (PD1) Antibody, APC
Catalog #: 136-25089
Human CD279 (PD1) Antibody [clone: 5D5], monoclonal. Validated for flow cytometry.
Product Description
Specifications
| Size | 25 tests, 100 tests |
| Estimated Lead Time | 1-2 business days |
| Species | Human |
| Host Species | Mouse |
| Accession Number | Q15116 |
| Gene Id | 5133 |
| Gene Symbols | PDCD1, PD1 |
| Protein Name / Synonyms | Programmed cell death protein 1 (Protein PD-1) (hPD-1) (CD antigen CD279) |
| Clonality | Monoclonal |
| Clone | 5D5 |
| Conjugation | APC |
| Preparation | The antibody was purified by affinity chromatography. |
| Format | Liquid |
| Concentration (lot specific) | 5 μl/test |
| Buffers | PBS, pH 7.2-7.4, 0.2% BSA, 0.1% sodium azide |
| Recommended Applications | Flow Cytometry |
| Research Area | Cardiovascular Disease, Cancer, Autoimmune Disease, Wnt-beta-Catenin Signaling |
| Excitation Laser | Red Laser, 633 nm |
| Maximum Emission Wavelength | 676 nm |
| Shipping Type | Blue ice |
| Storage | 4°C |
Description
Product Features
- Serum-free media used for cell culture of hybridomas to minimize bovine antibody contamination
- Gentle elution at pH 4.0 to minimize antibody degradation
- Protein A, G & L affinity purification
- High purity
Description
CD279 is a 55 kD member of the immunoglobulin superfamily and contains the immunoreceptor tyrosine-based inhibitory motif (ITIM) in the cytoplasmic region. CD279 plays a key role in peripheral tolerance and autoimmune disease and is expressed in activated T cells, B cells, and myeloid cells. The ligands of CD279 include PD-L1 and PD-L2, and there is evidence that these ligands have overlapping functions and expression in normal tissues.
Recommended Usage
Each lot of antibody has been tested by flow cytometry staining. Researchers are recommended to further titrate this antibody at the optimal concentration for each specific application.
Storage / Stability
Store at 2 °C ~ 8 °C, protected from prolonged light exposure. DO NOT FREEZE.