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Anti-Human CD279 (PD1) Antibody, Biotinylated
Catalog #: 136-01090
Human CD279 (PD1) Biotinylated Antibody [clone: 3B10], monoclonal Mouse IgG1, kappa. Validated for flow cytometry.
Product Description
Specifications
| Size | 100 µg, 500 µg |
| Estimated Lead Time | 3-5 business days |
| Species | Human |
| Host Species | Mouse |
| Clonality | Monoclonal |
| Clone | 3B10 |
| Conjugation | Biotin |
| Preparation | The antibody was purified by affinity chromatography, and conjugated with biotin. |
| Isotype | IgG1 Kappa |
| Format | Liquid |
| Concentration (lot specific) | 0.5 mg/mL |
| Buffers | PBS, pH 7.2-7.4, 0.2% BSA, 0.1% sodium azide |
| Recommended Applications | Flow Cytometry |
| Research Area | Cardiovascular Disease |
| Shipping Type | Blue ice |
| Storage | 4°C |
Description
Product Features
- Serum-free media used for cell culture of hybridomas to minimize bovine antibody contamination
- Gentle elution at pH 4.0 to minimize antibody degradation
- Protein A, G & L affinity purification
- High purity
Description
CD279 is a 55 kD member of the immunoglobulin superfamily and contains the immunoreceptor tyrosine-based inhibitory motif (ITIM) in the cytoplasmic region. CD279 plays a key role in peripheral tolerance and autoimmune disease and is expressed in activated T cells, B cells, and myeloid cells. The ligands of CD279 include PD-L1 and PD-L2, and there is evidence that these ligands have overlapping functions and expression in normal tissues.