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Anti-Human CD279 (PD1) Antibody, RayBright® Red 780
Catalog #: 136-27090
Human CD279 (PD1) Antibody [clone: 3B10], monoclonal mouse IgG1 kappa. Validated for flow cytometry.
Product Description
Specifications
| Size | 25 tests, 100 tests |
| Estimated Lead Time | 1-2 business days |
| Species | Human |
| Host Species | Mouse |
| Accession Number | Q15116 |
| Gene Id | 5133 |
| Gene Symbols | PDCD1, PD1 |
| Protein Name / Synonyms | Programmed cell death protein 1 (Protein PD-1) (hPD-1) (CD antigen CD279) |
| Clonality | Monoclonal |
| Clone | 3B10 |
| Conjugation | RayBright® Red 780 |
| Preparation | The antibody was purified by affinity chromatography. |
| Isotype | IgG1 Kappa |
| Format | Liquid |
| Concentration (lot specific) | 5 μl/test |
| Buffers | PBS, pH 7.2-7.4, 0.2% BSA, 0.1% sodium azide |
| Recommended Applications | Flow Cytometry |
| Research Area | Cardiovascular Disease, Cancer, Autoimmune Disease |
| Excitation Laser | Red Laser, 633 nm |
| Maximum Emission Wavelength | 780 nm, replace APC-Alexa Fluor™ 750 tandems |
| Shipping Type | Blue ice |
| Storage | 4°C |
Description
Product Features
- Serum-free media used for cell culture of hybridomas to minimize bovine antibody contamination
- Gentle elution at pH 4.0 to minimize antibody degradation
- Protein A, G & L affinity purification
- High purity
Description
CD279 is a 55 kD member of the immunoglobulin superfamily and contains the immunoreceptor tyrosine-based inhibitory motif (ITIM) in the cytoplasmic region. CD279 plays a key role in peripheral tolerance and autoimmune disease and is expressed in activated T cells, B cells, and myeloid cells. The ligands of CD279 include PD-L1 and PD-L2, and there is evidence that these ligands have overlapping functions and expression in normal tissues.
Recommended Usage
Each lot of antibody has been tested by flow cytometry staining. Researchers are recommended to further titrate this antibody at the optimal concentration for each specific application.
Storage / Stability
Store at 2 °C ~ 8 °C, protected from prolonged light exposure. DO NOT FREEZE.