CD56 is a member of the Ig superfamily. The ~140 kDa isoform of CD56 is considered the prototypic cell surface marker on human NK and NKT cells. CD56 is also expressed in the brain (cerebellum and cortex) and at neuromuscular junctions, certain large granular lymphocyte (LGL) leukemias, small-cell lung carcinomas, neuronal derived tumors, myelomas, and myeloid leukemias. CD56 mediates cell-cell and cell-matrix adhesion via homophilic and heterophilic interactions, respectively, and plays a role in activating intracellular signaling pathways.

Each lot of antibody has been tested by flow cytometry staining. Researchers are recommended to further titrate this antibody at the optimal concentration for each specific application.

Store at 2 °C ~ 8 °C, protected from prolonged light exposure. DO NOT FREEZE.