CD86 is the ligand for CD28 and CD154 (CTLA-4) and is expressed on activated B and T cells, monocytes/macrophages, dendritic cells, and astrocytes. CD86 has been shown to aid with triggering of NK cell-mediated cytotoxicity as well as immunoglobulin class-switching.

Each lot of antibody has been tested by flow cytometry staining. We suggest use ≤ 0.5 µg per million cells in 100 µl volume of staining buffer. Researchers are recommended to further titrate this antibody at the optimal concentration for each specific application.

Stored at 2 °C - 8 °C, protected from prolonged light exposure. DO NOT FREEZE.