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Anti-Human PD-L1 Antibody, Biotinylated
Catalog #: 136-01134
Human PD-L1 Biotinylated Antibody [clone: 4F3], monoclonal Mouse. Validated for flow cytometry.
Product Description
Specifications
| Size | 100 µg, 500 µg |
| Estimated Lead Time | 3-5 business days |
| Species | Human |
| Host Species | Mouse |
| Clonality | Monoclonal |
| Clone | 4F3 |
| Conjugation | Biotin |
| Preparation | The antibody was purified by affinity chromatography, and conjugated with biotin. |
| Format | Liquid |
| Concentration (lot specific) | 0.5 mg/mL |
| Buffers | PBS, pH 7.2-7.4, 0.2% BSA, 0.1% sodium azide |
| Recommended Applications | Flow Cytometry |
| Research Area | Cardiovascular Disease, Cancer, Cancer Immunology, Adaptive Immunity |
| Shipping Type | Blue ice |
| Storage | 4°C |
Description
Product Features
- Serum-free media used for cell culture of hybridomas to minimize bovine antibody contamination
- Gentle elution at pH 4.0 to minimize antibody degradation
- Protein A, G & L affinity purification
- High purity
Description
PD-L1 is a type I transmembrane glycoprotein which serves as one of the ligands for CD279 (PD1). Ther interactions between CD279 and its ligand can regulate the balance between the stimulatory and inhibitory signals required in response to microbes. PD-L1 is also partially responsible for costimulation of T cell proliferation although conflicting data suggests that it may also inhibit T cell proliferation and cytokine production.