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Anti-Human PD-L1 Antibody, PE
Catalog #: 136-18134
Human PD-L1 Antibody [clone: 4F3], monoclonal. Validated for flow cytometry.
Product Description
Specifications
| Size | 25 tests, 100 tests |
| Estimated Lead Time | 1-2 business days |
| Species | Human |
| Host Species | Mouse |
| Protein Name / Synonyms | PD-L1, CD274, B7-H1 |
| Clonality | Monoclonal |
| Clone | 4F3 |
| Conjugation | PE |
| Preparation | The antibody was purified by affinity chromatography. |
| Format | Liquid |
| Concentration (lot specific) | 5 μl/test |
| Buffers | PBS, pH 7.2-7.4, 0.2% BSA, 0.1% sodium azide |
| Recommended Applications | Flow Cytometry |
| Research Area | Cardiovascular Disease, Cancer, Cancer Immunology, Adaptive Immunity |
| Excitation Laser | Blue Laser, 488 nm / Green Laser, 561 nm |
| Maximum Emission Wavelength | 575 nm |
| Shipping Type | Blue ice |
| Storage | 4°C |
Description
Product Features
- Serum-free media used for cell culture of hybridomas to minimize bovine antibody contamination
- Gentle elution at pH 4.0 to minimize antibody degradation
- Protein A, G & L affinity purification
- High purity
Description
PD-L1 is a type I transmembrane glycoprotein which serves as one of the ligands for CD279 (PD1). Ther interactions between CD279 and its ligand can regulate the balance between the stimulatory and inhibitory signals required in response to microbes. PD-L1 is also partially responsible for costimulation of T cell proliferation although conflicting data suggests that it may also inhibit T cell proliferation and cytokine production.
Recommended Usage
Each lot of antibody has been tested by flow cytometry staining. Researchers are recommended to further titrate this antibody at the optimal concentration for each specific application.
Storage / Stability
Store at 2 °C ~ 8 °C, protected from prolonged light exposure. DO NOT FREEZE.