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Anti-Human PD-L1 Antibody, Purified
Catalog #: 136-00135
Human PD-L1 Antibody [clone: 1H11], monoclonal Mouse IgG1, kappa. Validated for flow cytometry.
Product Description
Specifications
| Size | 100 µg, 500 µg |
| Estimated Lead Time | 1-2 business days |
| Species | Human |
| Host Species | Mouse |
| Clonality | Monoclonal |
| Clone | 1H11 |
| Preparation | The antibody was purified by affinity chromatography. |
| Isotype | IgG1 Kappa |
| Format | Lyophilized |
| Concentration (lot specific) | Lyophilized |
| Buffers | PBS, pH 7.2-7.4; Carrier-free |
| Recommended Applications | Flow Cytometry |
| Reconstitution | Reconstitute in desired amount of PBS. |
| Research Area | Cardiovascular Disease, Cancer, Cancer Immunology, Adaptive Immunity |
| Shipping Type | Ambient temperature |
| Storage | -20°C |
Description
Product Features
- Serum-free media used for cell culture of hybridomas to minimize bovine antibody contamination
- Gentle elution at pH 4.0 to minimize antibody degradation
- Protein A, G & L affinity purification
- High purity
- Carrier free
- Endotoxin-free
Description
PD-L1 is a type I transmembrane glycoprotein which serves as one of the ligands for CD279 (PD1). Ther interactions between CD279 and its ligand can regulate the balance between the stimulatory and inhibitory signals required in response to microbes. PD-L1 is also partially responsible for costimulation of T cell proliferation although conflicting data suggests that it may also inhibit T cell proliferation and cytokine production.