PD-L1 is a type I transmembrane glycoprotein which serves as one of the ligands for CD279 (PD1). Ther interactions between CD279 and its ligand can regulate the balance between the stimulatory and inhibitory signals required in response to microbes. PD-L1 is also partially responsible for costimulation of T cell proliferation although conflicting data suggests that it may also inhibit T cell proliferation and cytokine production.

Each lot of antibody has been tested by flow cytometry staining. Researchers are recommended to further titrate this antibody at the optimal concentration for each specific application.

Store at 2 °C ~ 8 °C, protected from prolonged light exposure. DO NOT FREEZE.