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Anti-HUMAN-RIN1 (Y36) Antibody

Catalog #: 102-24028

Rabbit Anti-HUMAN-RIN1(Y36) Antibody, 400 µl

Product Description

Specifications

Size400 µL
Estimated Lead Time1-2 weeks
SpeciesHuman
Host SpeciesRabbit
Accession Number
Q13671
Gene Id
9610
Gene Symbols
RIN1
Protein Name / Synonyms
Ras and Rab interactor 1, Ras inhibitor JC99, Ras interaction/interference protein 1, RIN1
ClonalityPolyclonal
CloneRB46939
IsotypeKappa, Rabbit
Recommended ApplicationsWestern Blotting
Shipping TypeBlue ice
Storage-20°C

Description

Introduction

Ras effector protein, which may serve as an inhibitory modulator of neuronal plasticity in aversive memory formation. Can affect Ras signaling at different levels. First, by competing with RAF1 protein for binding to activated Ras. Second, by enhancing signaling from ABL1 and ABL2, which regulate cytoskeletal remodeling. Third, by activating RAB5A, possibly by functioning as a guanine nucleotide exchange factor (GEF) for RAB5A, by exchanging bound GDP for free GTP, and facilitating Ras-activated receptor endocytosis.

Other Information

Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Calculated Molecular Weight (Da)
84099
Antigen Source
Human

Images

WB (1:1000)

Western blot analysis of lysate from U-87 MG cell line, using HUMAN-RIN1(Y36) antibody (Cat. #102-24028). 102-24028 was diluted at 1:1000. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody. Lysate at 35ug.

WB

Storage/Stability

2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.