Anti-IBSP (N-term) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	P21815
Gene Id	3381
Gene Symbols	IBSP
Protein Name / Synonyms	IBSP (N-term)
Clonality	Polyclonal
Preparation	This IBSP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 70-99 amino acids from the N-terminal region of human IBSP.
Concentration (lot specific)	0.5 mg/ml
Recommended Applications	Western Blotting
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

The protein encoded by this gene is a major structural protein of the bone matrix. It constitutes approximately 12% of the noncollagenous proteins in human bone and is synthesized by skeletal-associated cell types, including hypertrophic chondrocytes, osteoblasts, osteocytes, and osteoclasts. The only extraskeletal site of its synthesis is the trophoblast. This protein binds to calcium and hydroxyapatite via its acidic amino acid clusters, and mediates cell attachment through an RGD sequence that recognizes the vitronectin receptor.

Specificity

Other Names

IBSP; BNSP; Bone sialoprotein 2; Bone sialoprotein II; Cell-binding sialoprotein; Integrin-binding sialoprotein

NCBI Accession #

NP_004958.2

Other Accession #

NP_004958.2

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

35148

Recommended Dilutions

WB: 1:1000

IBSP Antibody (N-term) (Cat# 102-12316) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the IBSP antibody detected the IBSP protein (arrow).

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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