Anti-IGF1 (C-term) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	P05019
Gene Id	3479
Gene Symbols	IGF1
Protein Name / Synonyms	IGF1 (C-term)
Clonality	Polyclonal
Preparation	This IGF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 115-144 amino acids from the C-terminal region of human IGF1.
Concentration (lot specific)	0.500 mg/ml
Recommended Applications	Western Blotting, IF, FC, IHC-P
Research Area	Cancer, Inflammation
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

The protein encoded by this gene is similar to insulin in function and structure and is a member of a family of proteins involved in mediating growth and development. The encoded protein is processed from a precursor, bound by a specific receptor, and secreted. Defects in this gene are a cause of insulin-like growth factor I deficiency. Several transcript variants encoding different isoforms have been found for this gene.

Specificity

Other Names

IGF1; IBP1; Insulin-like growth factor I; Mechano growth factor; Somatomedin-C

NCBI Accession #

NP_000609.1;NP_001104754.1;NP_001104755.1

Other Accession #

P01343; NP_000609.1

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

21841

Recommended Dilutions

WB: 1:1000; IF: 1:10-50; FC: 1:10-50; IHC: 1:10-50

	IGF1 Antibody (C-term) (Cat# 102-12304) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the IGF1 antibody detected the IGF1 protein (arrow).
	Confocal immunofluorescent analysis of IGF1 Antibody (C-term)(Cat# 102-12304) with A549 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green).DAPI was used to stain the cell nuclear (blue).
	IGF1 Antibody (C-term) (Cat# 102-12304) flow cytometric analysis of A549 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
	IGF1 Antibody (C-term) (Cat# 102-12304)immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of IGF1 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
	IGF1 Antibody (C-term) (Cat# 102-12304)immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of IGF1 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.