Anti-IGFBP3 (N-term) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	P17936
Gene Id	3486
Gene Symbols	IGFBP3
Protein Name / Synonyms	IGFBP3 (N-term)
Clonality	Polyclonal
Preparation	This IGFBP3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 163-193 amino acids from the N-terminal region of human IGFBP3.
Concentration (lot specific)	1.630 mg/ml
Recommended Applications	Western Blotting, IHC-P
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

IGFBP3 is a member of the insulin-like growth factor binding protein (IGFBP) family with an IGFBP domain and a thyroglobulin type-I domain. The protein forms a ternary complex with insulin-like growth factor acid-labile subunit (IGFALS) and either insulin-like growth factor (IGF) I or II. In this form, it circulates in the plasma, prolonging the half-life of IGFs and altering their interaction with cell surface receptors.

Specificity

Predicted Reactivity

Rat

Other Names

IGFBP3; IBP3; Insulin-like growth factor-binding protein 3

NCBI Accession #

NP_000589.2;NP_001013416.1

Other Accession #

P15473

Format

Type

Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

31674

Recommended Dilutions

WB: 1:1000; IHC: 1:10-50

	Western blot analysis of anti-IGFBP3 Antibody (N-term) (Cat# 102-17504) in HepG2 cell line lysates (35ug/lane). IGFBP3(arrow) was detected using the purified Pab.
	Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with IGFBP3 Antibody (N-term) (Cat# 102-17504), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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