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Anti-IGFBP6 Antibody
Catalog #: 130-10065
Rabbit Anti-Human IGFBP6 Antibody
Product Description
Specifications
| Size | 20 µg, 100 µg, 200 µg, 500 µg |
| Estimated Lead Time | 1-2 business days |
| Species | Human |
| Accession Number | P24592 |
| Clonality | Polyclonal |
| Immunogen | The Immunogen was recombinant protein derived from human IGFBP6. This antibody was produced from a rabbit immunized with the immunogen. The IgG fraction was purified from rabbit serum followed by Protein A/G affinity chromatography. |
| Recommended Applications | ELISA (recommended work dilution= 1: 32, 000) |
| Antigen Catalog Number | 230-00045 |
| Reconstitution | Product is supplied as a powder obtained from lyophilization of purified antibody in PBS without preservatives. Reconstitute the antibody with sterile water to a final concentration of 1 mg/ml. |
| Shipping Type | Ambient temperature |
| Storage | -20°C |
Description
Description
The insulin-like growth factor binding proteins (IGFBP) is a large family including six high affinity IGF binding proteins and four low affinity binding proteins. The cysteine-rich IGFBPs play a role in lipoprotein assembly and dietary cholesterol absorption. In addition, IGF-binding proteins prolong thehalf-life of the IGFs, inhibit or stimulate the growth promoting effects of the IGFs on cell culture, and alter the interaction of IGFs with their cell surface receptors.
Specificity
This antibody binds to Human IGFBP6. Cross reactivity with mouse and rat IGFBP6 was not tested.
Storage
Store at 4°C if intended for use within one month, otherwise, store at -20°C to -80°C. The lyophilized antibody is stable for at least 18 months after the date of receipt when stored at -20°C to -80°C. After reconstitution, it can be aliquoted and stored frozen at -20°C to -80°C in a manual defrost freezer for at least 6 months without detectable loss of activity. Upon reconstitution, the antibody can also be stored for 1 month at 4°C. Please avoid freeze-thaw cycles, as this will lower the activity of the antibody.
Related Products
Goat Anti-Insulin-like Growth Factor Binding Protein 6 (catalog #: ER-14-0735 ) Recombinant Human Insulin-like Growth Factor Binding Protein 6(catalog #: 230-00045)
References
- Yu H, et al.. (1999) Insulin-like growth factors (IGF-I, free IGF-I and IGF-II) and insulin-like growth factor binding proteins (IGFBP-2, IGFBP-3, IGFBP-6, and ALS) in blood circulation. J Clin Lab Anal. 13(4):166-72.
- Wegmann BR, et al.. (1993) Molecular cloning of IGFBP-5 from SCLC cell lines and expression of IGFBP-4, IGFBP-5 and IGFBP-6 in lung cancer cell lines and primary tumours. Eur J Cancer. 29A(11):1578-84.
Expiration:
12 months from the date of shipment when stored properly.