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Anti-IGFBP6 Antibody, Biotinylated
Catalog #: 130-10065B-50
Rabbit anti-IGFBP6 Biotinylated Antibody, 50 ug
Product Description
Specifications
| Size | 50 µg |
| Estimated Lead Time | 1-2 business days |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | P24592 |
| Clonality | Polyclonal |
| Immunogen | The Immunogen was recombinant protein derived from human IGFBP6. This antibody was produced from a rabbit immunized with the immunogen. The IgG fraction was purified from rabbit serum followed by Protein A/G affinity chromatography. |
| Isotype | IgG |
| Recommended Applications | ELISA (recommended work dilution= 1: 32, 000) |
| Reconstitution | A separate vial of dilution buffer is provided for reconstitution. The antibody is supplied lyophilized, originally containing PBS, without preservative stabilizers (e.g. sodium azide). The final amount is indicated on the shipping vial. |
| Shipping Type | Ambient temperature |
| Storage | -20°C |
Description
Description
The insulin-like growth factor binding proteins (IGFBP) is a large family including six high affinity IGF binding proteins and four low affinity binding proteins. The cysteine-rich IGFBPs play a role in lipoprotein assembly and dietary cholesterol absorption. In addition, IGF-binding proteins prolong thehalf-life of the IGFs, inhibit or stimulate the growth promoting effects of the IGFs on cell culture, and alter the interaction of IGFs with their cell surface receptors.
Storage / Stability
The antibody is stable for at least 1 year from the date of receipt when stored at -20°C to -70°C. Reconstituted antibody can also be aliquotted and stored at 4°C for 1 month or at -20°C to -70°C in a manual defrost freezer for many months without detectable loss activity. Please avoid freeze-thaw cycles.
Specificity
This antibody binds to Human IGFBP6. Cross reactivity with mouse and rat IGFBP6 was not tested.
Related Products
Goat Anti-Insulin-like Growth Factor Binding Protein 6 (catalog #: ER-14-0735 ) Recombinant Human Insulin-like Growth Factor Binding Protein 6(catalog #: 230-00045)
References
- Yu H, et al.. (1999) Insulin-like growth factors (IGF-I, free IGF-I and IGF-II) and insulin-like growth factor binding proteins (IGFBP-2, IGFBP-3, IGFBP-6, and ALS) in blood circulation. J Clin Lab Anal. 13(4):166-72.
- Wegmann BR, et al.. (1993) Molecular cloning of IGFBP-5 from SCLC cell lines and expression of IGFBP-4, IGFBP-5 and IGFBP-6 in lung cancer cell lines and primary tumours. Eur J Cancer. 29A(11):1578-84.
Expiration:
12 months from the date of shipment when stored properly.