Anti-Ikaros (C-terminus) Antibody

Product Description

Specifications

Size	100 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Mouse
Accession Number	Q13422
Gene Id	10320
Gene Symbols	IKZF1
Protein Name / Synonyms	CLL associated antigen KW 6;DNA-binding protein Ikaros;hIk 1;hIk-1;Hs.54452;IK1;Ikaros (zinc finger protein);IKAROS;IKAROS family zinc finger 1 (Ikaros);Ikaros family zinc finger protein 1;Ikzf1;IKZF1_HUMAN;LYF1;Lymphoid transcription factor LyF-1;PRO0758;Zinc finger protein subfamily 1A 1 (Ikaros);zinc finger protein subfamily 1A 1;Zinc finger protein, subfamily 1A, member 1;ZNFN1A1.
Clonality	Monoclonal
Recommended Applications	Western Blotting, IP
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

Transcription regulator of hematopoietic cell differentiation. Binds gamma-satellite DNA. Binds with higher affinity to gamma satellite A. Plays a role in the development of lymphocytes, B- and T-cells. Binds and activates the enhancer (delta-A element) of the CD3-delta gene. Repressor of the TDT (terminal deoxynucleotidyltransferase) gene during thymocyte differentiation. Regulates transcription through association with both HDAC-dependent and HDAC-independent complexes. Targets the 2 chromatin-remodeling complexes, NuRD and BAF (SWI/SNF), in a single complex (PYR complex), to the beta-globin locus in adult erythrocytes. Increases normal apoptosis in adult erythroid cells. Confers early temporal competence to retinal progenitor cells (RPCs) (By similarity).

Other Information

Antigen Type

Recombinant Protein

Images

WB (1:1000)

Western blot detection of Ikaros(C-terminus) in Ramos and Jurkat cell lysates using Ikaros(C-terminus) mouse mAb (1:1000 diluted).Predicted band size: 58KDa.Observed band size: 58KDa.

IP (0.388888888889)

Immunoprecipitation analysis of Hela cell lysate using Ikaros (C-terminus) mouse mAb.

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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