Rabbit Anti-Human IKK beta Antibody, 400 ul
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Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | O14920 |
| Gene Id | 3551 |
| Gene Symbols | IKBKB |
| Protein Name / Synonyms | IKK beta |
| Clonality | Polyclonal |
| Preparation | This IKK beta antibody is generated from rabbits immunized with recombinant human IKK beta (full length sequence). |
| Concentration (lot specific) | 2.0 mg/ml |
| Recommended Applications | Western Blotting, IHC-P, IF |
| Research Area | Cancer, Inflammation, NFkB Signaling |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
This gene encodes a member of the serine/threonine protein kinase family. The encoded protein, a component of a cytokine-activated protein complex that is an inhibitor of the essential transcription factor NF-kappa-B complex, phosphorylates sites that trigger the degradation of the inhibitor via the ubiquination pathway, thereby activating the transcription factor.
Specificity
Other Names
IKBKB; IKKB; Inhibitor of nuclear factor kappa-B kinase subunit beta; I-kappa-B kinase 2; Nuclear factor NF-kappa-B inhibitor kinase beta
NCBI Accession #
NP_001177649.1;NP_001229707.1;NP_001547.1
Format
Type
Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
86564
Recommended Dilutions
WB: 1:1000; IHC: 1:50-100; IF: 1:10-50
 | Western blot analysis of anti-IKK beta Antibody (Cat# 102-17807) in Hela cell line lysates (35ug/lane). IKK beta(arrow) was detected using the purified Pa). |
 | Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with IKK beta antibody (Cat# 102-17807), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. |
 | Confocal immunofluorescent analysis of IKK beta Antibody(Cat# 102-17807) with Hela cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). Actin filaments have been labeled with Alexa Fluor 555 phalloidin (red).DAPI was used to stain the cell nuclear (blue). |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.