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Anti-IL-6 Antibody
Catalog #: 130-10058
Mouse Anti-Human IL-6 (2A8-D8-C3) Antibody
Product Description
Specifications
| Size | 20 µg, 100 µg, 200 µg, 500 µg, 1 mg |
| Estimated Lead Time | 1-2 business days |
| Species | Human |
| Host Species | Mouse |
| Accession Number | P05231 |
| Gene Id | 3569 |
| Gene Symbols | IL6 IFNB2 |
| Protein Name / Synonyms | Interleukin-6 (IL-6) (B-cell stimulatory factor 2) (BSF-2) (CTL differentiation factor) (CDF) (Hybridoma growth factor) (Interferon beta-2) (IFN-beta-2) |
| Clonality | Monoclonal |
| Clone | 2A8-D8-C3 |
| Preparation | Immunogen was recombinant of human IL-6 protein. This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with the immunogen. The IgG fraction of tissue culture supernatant was purified by Protein G/A affinity chromatography. |
| Isotype | IgG |
| Recommended Applications | ELISA (recommended work dilution= 1:64, 000) |
| Reconstitution | Product is supplied as a powder obtained from lyophilization of purified antibody in glycine solution. Reconstitute the antibody with sterile water to a final concentration of 1 mg/ml. |
| Research Area | Angiogenesis, Cardiovascular Disease, Cancer, Inflammation |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Description
Interleukin-6 (IL-6) is an interleukin, secreted by T cells and macrophages to stimulate immune response to trauma. IL-6 is an anti-inflammatory cytokine mediating through its inhibitory effects on IL-1 and TNF-alpha, and its activation of IL10 and IL-1ra. Interleukin 6 interacts with IL-6 receptor and glycoprotein 130. IL-6 mediates fever and the acute phase response, and involves in many disease processes, such as prostate cancer, depression, atherosclerosis, diabetes, and rheumatoid arthritis. Metastatic cancer patients have higher blood IL-6.
Storage/Stability
Store at -20°C. If intended for use within a month, may keep at 4°C. Minimize freeze-thaw cycles.
Expiration
12 months from the date of shipment when stored properly.