3607 Parkway Ln Ste 200 Norcross, Georgia 30092
www.RayBiotech.com | info@raybiotech.com
770-729-2992 | +1-888-494-8555
ISO 13485:2016 cGMP
Anti-IL-6 Antibody
Catalog #: 130-10132
Mouse Anti-Human IL-6 Antibody
Product Description
Specifications
| Size | 20 µg, 100 µg, 200 µg, 500 µg |
| Estimated Lead Time | 1-2 business days |
| Species | Human |
| Accession Number | AAH15511 |
| Clonality | Monoclonal |
| Immunogen | Immunogen was recombinant protein derived from Human IL-6. This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with the immunogen. The IgG fraction of tissue culture supernatant was purified by Protein A/G affinity chromatography. |
| Recommended Applications | ELISA (recommended work dilution= 1: 160, 000) |
| Antigen Catalog Number | 230-00011 |
| Reconstitution | Product is supplied as a powder obtained from lyophilization of purified antibody in PBS without preservatives. Reconstitute the antibody with sterile water to a final concentration of 1 mg/ml. |
| Research Area | Cardiovascular Disease, Inflammation |
| Shipping Type | Ambient temperature |
| Storage | -20°C |
Description
Description
Interleukin-6 (IL-6) is an interleukin, secreted by T cells and macrophages to stimulate immune response to trauma. IL-6 is an anti-inflammatory cytokine mediating through its inhibitory effects on IL-1 and TNF-alpha, and its activation of IL10 and IL-1ra. Interleukin 6 interacts with IL-6 receptor and glycoprotein 130. IL-6 mediates fever and the acute phase response, and involves in many disease processes, such as prostate cancer, depression, atherosclerosis, diabetes, and rheumatoid arthritis. Metastatic cancer patients have higher blood IL-6.
Specificity
This antibody binds to its immunogen, and did not show any cross reactivity with unrelated antigens in ELISA. Cross reactivity with mouse and rat IL6 has not been tested yet.
Storage
Store at 4°C if intended for use within one month, otherwise, store at -20°C to -80°C. The lyophilized antibody is stable for at least 18 months after the date of receipt when stored at -20°C to -80°C. After reconstitution, it can also be aliquoted and stored frozen at -20°C to -80°C in a manual defrost freezer for 6 months without detectable loss of activity. Upon reconstitution, the antibody can also be stored for 30 days at 4°C. Please avoid freeze-thaw cycles, as this will lower the activity of the antibody.
Expiration:
12 months from the date of shipment when stored properly.