Interleukin-6 (IL-6) is an interleukin, secreted by T cells and macrophages to stimulate immune response to trauma. IL-6 is an anti-inflammatory cytokine mediating through its inhibitory effects on IL-1 and TNF-alpha, and its activation of IL10 and IL-1ra. Interleukin 6 interacts with IL-6 receptor and glycoprotein 130. IL-6 mediates fever and the acute phase response, and is involved in many disease processes, such as prostate cancer, depression, atherosclerosis, diabetes, and rheumatoid arthritis.Metastatic cancer patients have higher blood IL-6.

The antibody is stable for at least 1 year from the date of receipt when stored at -20°C to -70°C. Reconstituted antibody can also be aliquotted and stored at 4°C for 1 month or at -20°C to -70°C in a manual defrost freezer for many months without detectable loss activity. Please avoid freeze-thaw cycles.

The mouse anti-human IL-6 antibody detects targets specifically derived from human recombinant protein at various concentrations. Cross reactivity with mouse and rat are expected from sequence similarity. The antibody specifically binds to its immunogen and did not show any cross reactivity with unrelated antigens in ELISA. The specificity for binding to recombinant protein, cellular protein and native antigen is not defined.