Anti-IL-8 / CXCL8 Antibody

Catalog #: DS-PB-01141

Rabbit Anti-Human IL-8 / CXCL8

Product Description

Specifications

Size	0.1 mg
Estimated Lead Time	1-2 weeks
Species	Human
Specificity	This product is specific for human IL-8 (Interleukin-8), a 72 amino acid pro-inflammatory CXC chemokine designated CXCL8, secreted by endothelial cells and monocytes, which acts as a major chemoattractant for neutrophils and also T cells and basophils. IL-8, first isolated from osteosarcoma cells, contains the ELR-motif (N-terminal Glu-Leu-Arg amino acid sequence) and signals through the CXCR1 and CXCR2 receptors. Cancer studies have demonstrated a role for IL-8 in the angiogenesis and growth of tumours. Previous nomenclature for IL-8 includes neutrophil activating protein 1(NAP-1), granulocyte chemotactic protein 1 (GCP-1), Monocyte-derived neutrophil-activating peptide (MONAP) and protein 3-10C.
Host Species	Rabbit
Protein Name / Synonyms	IL-8 / CXCL8
Preparation	Antisera to human IL-8 were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG prepared by affinity chromatography.
Concentration (lot specific)	IgG concentration 1.0 mg/ml
Recommended Applications	ELISA (dilution: 0.1, 0.2ug/ml), Immunofluorescence, Immunohistology - Paraffin, Western Blotting
Reconstitution	Reconstitute with 0.1 ml distilled water
Research Area	Inflammation, Chemokine Biology
Shipping Type	Ambient temperature
Storage	-20°C

Description

The addition of 0.09% sodium azide is recommended for long term storage.

Storage/Stability

Prior to reconstitution store at +4 °C. Following reconstitution store at -20 °C.

This product should be stored undiluted.

Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 12 months after receipt.

Format

Supplied as:

Purified IgG - lyophilized

Formulation:

Phosphate buffered saline

Reconstitution:

Reconstitute with 0.1 ml distilled water

Format Type:

Purified

Preparation

Antisera to human IL-8 were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG prepared by affinity chromatography.

Immunogen:

Recombinant human IL-8

Preservative:

None present

Expiration:

12 months from the date of shipment when stored properly.

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