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Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | O95256 |
| Gene Id | 8807 |
| Gene Symbols | IL18RAP |
| Protein Name / Synonyms | IL18RAP (N-term) |
| Clonality | Polyclonal |
| Preparation | This IL18RAP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 73-101 amino acids from the N-terminal region of human IL18RAP. |
| Concentration (lot specific) | 0.5 mg/ml |
| Recommended Applications | Western Blotting, IHC-P, FC |
| Research Area | Inflammation, Ras/Rap Signaling |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
IL18RAP is required for the high affinity binding of interleukin 18 (IL-18) to its receptor complex (By similarity). Together with IL18R1 mediates IL-18-dependent activation of NF-kappa-B and JNK.
Specificity
Other Names
IL18RAP; IL1R7; Interleukin-18 receptor accessory protein; Accessory protein-like; CD218 antigen-like family member B; CDw218b; IL-1R accessory protein-like; Interleukin-1 receptor 7; Interleukin-18 receptor accessory protein-like; Interleukin-18 receptor beta; CD_antigen=CD218b; Flags: Precursor
NCBI Accession #
NP_003844.1
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
68310
Recommended Dilutions
WB: 1:1000; IHC: 1:10-50; FC: 1:10-50
 | Western blot analysis of IL18RAP Antibody (N-term) (Cat# 102-18034) in K562 cell line lysates (35ug/lane). IL18RAP (arrow) was detected using the purified Pab. |
 | Formalin-fixed and paraffin-embedded human lung carcinoma reacted with IL18RAP Antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. |
 | IL18RAP Antibody (N-term)(Cat# 102-18034) flow cytometric analysis of k562 cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.