Anti-IL1B (Center) (Ascites) Antibody

Product Description

Specifications

Size	0.1 mL
Estimated Lead Time	1-2 weeks
Species	Human
Accession Number	P01584
Gene Id	3553
Gene Symbols	IL1B
Protein Name / Synonyms	IL1B (Center) (Ascites)
Clonality	Monoclonal
Preparation	This IL1B antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 148-174 amino acids from the Central region of human IL1B.
Recommended Applications	Western Blotting
Research Area	Angiogenesis, Inflammation
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. [provided by RefSeq].

Specificity

Predicted Reactivity

Monkey, Rabbit

Other Names

IL1B; IL1F2; Interleukin-1 beta; Catabolin

NCBI Accession #

NP_000567.1

Other Accession #

P14628; P79182; NP_000567.1

Format

Type

Mouse Monoclonal Antibody (Mab)

Calculated Molecular Weight (Da)

30748

Recommended Dilutions

WB: 1:2000-4000

IL1B Antibody (Center)(Ascites)(Cat# 102-10345). 293 cell lysates transiently transfected with the IL1B gene.

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

Featured Products