Anti-IL1R (C-term E487) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	P14778
Gene Id	3554
Gene Symbols	IL1R1
Protein Name / Synonyms	IL1R (C-term E487)
Clonality	Polyclonal
Preparation	This IL1R antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 474-503 amino acids from the C-terminal region of human IL1R.
Concentration (lot specific)	0.368 mg/ml
Recommended Applications	Western Blotting, IHC-P
Research Area	Inflammation
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

IL1R is a member of the interleukin 1 receptor family. An experiment with transient gene expression demonstrated that this receptor was incapable of binding to interleukin 1 alpha and interleukin 1 beta with high affinity. IL1R is a receptor for interleukin 1 family member 9 (IL1F9). Binding to the agonist leads to the activation of NF-kappa-B. The gene for this protein and four other interleukin 1 receptor family genes, including interleukin 1 receptor, type I (IL1R1), interleukin 1 receptor, type II (IL1R2), interleukin 1 receptor-like 1 (IL1RL1), and interleukin 18 receptor 1 (IL18R1), form a cytokine receptor gene cluster in a region mapped to chromosome 2q12.

Specificity

Predicted Reactivity

Rat

Other Names

IL1R1; IL1R; IL1RA; IL1RT1; Interleukin-1 receptor type 1; CD121 antigen-like family member A; Interleukin-1 receptor alpha; Interleukin-1 receptor type I; p80; CD_antigen=CD121a; Interleukin-1 receptor type 1, membrane form; Interleukin-1 receptor type 1, soluble form

NCBI Accession #

NP_000868.1

Other Accession #

Q02955

Format

Type

Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

65402

Recommended Dilutions

WB: 1:1000; IHC: 1:10-50

	Western blot analysis of anti-IL1R (Cat# 102-16757) in HL60 cell line lysates (35ug/lane). IL1R (arrow) was detected using the purified Pab.
	Formalin-fixed and paraffin-embedded human prostata carcinoma tissue reacted with IL1R antibody (C-term E487), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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