Anti-IL21 (C-term) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	Q9HBE4
Gene Id	59067
Gene Symbols	IL21
Protein Name / Synonyms	IL21 (C-term)
Clonality	Polyclonal
Preparation	This IL21 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 104-132 amino acids from the C-terminal region of human IL21.
Concentration (lot specific)	0.350 mg/ml
Recommended Applications	Western Blotting
Research Area	Inflammation
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

Cytokine with immunoregulatory activity. May promote the transition between innate and adaptive immunity. Induces the production of IgG(1) and IgG(3) in B-cells (By similarity). May play a role in proliferation and maturation of natural killer (NK) cells in synergy with IL15. May regulate proliferation of mature B-and T-cells in response to activating stimuli. In synergy with IL15 and IL18 stimulates interferon gamma production in T-cells and NK cells. During T-cell mediated immune response may inhibit dendritic cells (DC) activation and maturation.

Specificity

Other Names

IL21; Interleukin-21; Za11

NCBI Accession #

NP_001193935.1;NP_068575.1

Other Accession #

NP_068575.1

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

17923

Recommended Dilutions

WB: 1:1000

	IL21 Antibody (C-term) (Cat# 102-12188) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the IL21 antibody detected the IL21 protein (arrow).
	Western blot analysis of IL21 (arrow) using rabbit polyclonal IL21 Antibody (C-term) (Cat# 102-12188). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the IL21 gene.

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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