Anti-IL6 (Center) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	P05231
Gene Id	3569
Gene Symbols	IL6
Protein Name / Synonyms	IL6 (Center)
Clonality	Polyclonal
Preparation	This IL6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 27-55 amino acids from the Central region of human IL6.
Concentration (lot specific)	0.440 mg/ml
Recommended Applications	Western Blotting, FC, IHC-P
Research Area	Angiogenesis, Cardiovascular Disease, Cancer, Inflammation
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

This gene encodes a cytokine that functions in inflammation and the maturation of B cells. The protein is primarily produced at sites of acute and chronic inflammation, where it is secreted into the serum and induces a transcriptional inflammatory response through interleukin 6 receptor, alpha. The functioning of this gene is implicated in a wide variety of inflammation-associated disease states, including suspectibility to diabetes mellitus and systemic juvenile rheumatoid arthritis.

Specificity

Other Names

IL6; IFNB2; Interleukin-6; B-cell stimulatory factor 2; CTL differentiation factor; Hybridoma growth factor; Interferon beta-2

NCBI Accession #

NP_000591.1

Other Accession #

NP_000591.1

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

23718

Recommended Dilutions

WB: 1:1000; FC: 1:10-50; IHC: 1:10-50

	IL6 Antibody (Center) (Cat# 102-11587) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the IL6 antibody detected the IL6 protein (arrow).
	IL6 Antibody (Center) (Cat# 102-11587) flow cytometric analysis of NCI-H460 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
	IL6 Antibody (Center) (102-11587)immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of IL6 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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