Anti-ILK (S343) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	Q13418
Gene Id	3611
Gene Symbols	ILK
Protein Name / Synonyms	ILK (S343)
Clonality	Polyclonal
Preparation	This ILK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 321-350 amino acids from human ILK.
Concentration (lot specific)	0.350 mg/ml
Recommended Applications	Western Blotting
Research Area	Cancer
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

Transduction of extracellular matrix signals through integrins influences intracellular and extracellular functions, and appears to require interaction of integrin cytoplasmic domains with cellular proteins. Integrin-linked kinase (ILK), interacts with the cytoplasmic domain of beta-1 integrin. ILK is a serine/threonine protein kinase with 4 ankyrin-like repeats, which associates with the cytoplasmic domain of beta integrins and acts as a proximal receptor kinase regulating integrin-mediated signal transduction.

Specificity

Predicted Reactivity

Mouse, Rat, Bovine

Other Names

ILK; ILK1; ILK2; Integrin-linked protein kinase; 59 kDa serine/threonine-protein kinase; ILK-1; ILK-2; p59ILK

NCBI Accession #

NP_001014794.1;NP_001014795.1;NP_001265370.1;NP_004508.1

Other Accession #

Q99J82; O55222; Q3SWY2; NP_004508

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

51419

Recommended Dilutions

WB: 1:1000

Western blot analysis of ILK-pS343 antibody (Cat# 102-17520) in MDA-MB435 cell line lysates (35ug/lane). ILK (arrow) was detected using the purified Pab.

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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