Anti-IMPDH1 (C-term) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	P20839
Gene Id	3614
Gene Symbols	IMPDH1
Protein Name / Synonyms	IMPDH1 (C-term)
Clonality	Polyclonal
Preparation	This IMPDH1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 487-514 amino acids from the C-terminal region of human IMPDH1.
Concentration (lot specific)	0.430 mg/ml
Recommended Applications	Western Blotting, IF, IHC-P
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

The protein encoded by this gene acts as a homotetramer to regulate cell growth. The encoded protein is an enzyme that catalyzes the synthesis of xanthine monophosphate (XMP) from inosine-5'-monophosphate (IMP). This is the rate-limiting step in the de novo synthesis of guanine nucleotides. Defects in this gene are a cause of retinitis pigmentosa type 10 (RP10). Several transcript variants encoding different isoforms have been found for this gene.

Specificity

Predicted Reactivity

Mouse, Rat, Bovine

Other Names

IMPDH1; IMPD1; Inosine-5'-monophosphate dehydrogenase 1; IMPDH-I

NCBI Accession #

NP_000874.2;NP_001096075.1;NP_001136045.1;NP_001136046.1;NP_001136047.1;NP_001136048.1;NP_899066.1

Other Accession #

D3ZLZ7; P50096; A0JNA3; NP_001136045.1; NP_001096075.1

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

55406

Recommended Dilutions

WB: 1:1000; IF: 1:10-50; IHC: 1:10-50

	IMPDH1 Antibody (C-term) (Cat# 102-12053) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the IMPDH1 antibody detected the IMPDH1 protein (arrow).
	Confocal immunofluorescent analysis of IMPDH1 Antibody (C-term) (Cat# 102-12053) with Hela cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).
	IMPDH1 Antibody (C-term) (102-12053)immunohistochemistry analysis in formalin fixed and paraffin embedded human breast carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of IMPDH1 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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