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Anti-IMPDH1 (N-term) Antibody

Catalog #: 102-12606

Rabbit Anti-Human IMPDH1 (N-term) Antibody, 400 ul

Product Description

Specifications

Size400 µL
Estimated Lead Time1-2 weeks
SpeciesHuman
Host SpeciesRabbit
Accession Number
P20839
Gene Id
3614
Gene Symbols
IMPDH1
Protein Name / Synonyms
IMPDH1 (N-term)
ClonalityPolyclonal
PreparationThis IMPDH1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 84-113 amino acids from the N-terminal region of human IMPDH1.
Concentration (lot specific)
0.5 mg/ml
Recommended ApplicationsWestern Blotting, IHC-P
Shipping TypeBlue ice
Storage-20°C

Description

Introduction

The protein encoded by this gene acts as a homotetramer to regulate cell growth. The encoded protein is an enzyme that catalyzes the synthesis of xanthine monophosphate (XMP) from inosine-5'-monophosphate (IMP). This is the rate-limiting step in the de novo synthesis of guanine nucleotides. Defects in this gene are a cause of retinitis pigmentosa type 10 (RP10). Several transcript variants encoding different isoforms have been found for this gene.

Specificity

Predicted Reactivity
Mouse, Rat, Zebrafish, Bovine
Other Names
IMPDH1; IMPD1; Inosine-5'-monophosphate dehydrogenase 1; IMPDH-I
NCBI Accession #
NP_000874.2;NP_001096075.1;NP_001136045.1;NP_001136046.1;NP_001136047.1;NP_001136048.1;NP_899066.1
Other Accession #
D3ZLZ7; P50096; Q6GMG5; A0JNA3; NP_001136045.1; NP_899066.1; NP_001096075.1

Format

Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
55406
Recommended Dilutions
WB: 1:1000; IHC: 1:10-50
IMPDH1 Antibody (N-term) (Cat# 102-12606) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the IMPDH1 antibody detected the IMPDH1 protein (arrow).
IMPDH1 Antibody (N-term) (102-12606)immunohistochemistry analysis in formalin fixed and paraffin embedded human breast tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of IMPDH1 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.