Rabbit Anti-Human IRF4 (Center) Antibody, 400 ul
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Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | Q15306 |
| Gene Id | 3662 |
| Gene Symbols | IRF4 |
| Protein Name / Synonyms | IRF4 (Center) |
| Clonality | Polyclonal |
| Preparation | This IRF4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 164-191 amino acids from the Central region of human IRF4. |
| Concentration (lot specific) | 2.0 mg/ml |
| Recommended Applications | Western Blotting, FC |
| Research Area | Cancer |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
The protein encoded by this gene belongs to the IRF (interferon regulatory factor) family of transcription factors, characterized by an unique tryptophan pentad repeat DNA-binding domain. The IRFs are important in the regulation of interferons in response to infection by virus, and in the regulation of interferon-inducible genes. This family member is lymphocyte specific and negatively regulates Toll-like-receptor (TLR) signaling that is central to the activation of innate and adaptive immune systems. A chromosomal translocation involving this gene and the IgH locus, t(6;14)(p25;q32), may be a cause of multiple myeloma. Alternatively spliced transcript variants have been found for this gene.
Specificity
Other Names
IRF4; MUM1; Interferon regulatory factor 4; Lymphocyte-specific interferon regulatory factor; Multiple myeloma oncogene 1; NF-EM5
NCBI Accession #
NP_001182215.1;NP_002451.2
Other Accession #
NP_001182215.1; NP_002451.2
Format
Type
Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
51772
Recommended Dilutions
WB: 1:1000; FC: 1:10-50
 | Western blot analysis of IRF4 (arrow) using rabbit polyclonal IRF4 Antibody (Center) (Cat# 102-11668). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the IRF4 gene. |
 | IRF4 Antibody (Center) (Cat# 102-11668) flow cytometric analysis of 293 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.