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Anti-IRF7 (C-term) Antibody
Catalog #: DS-PB-01180
Rabbit Anti-Human IRF7 (C-term)
Product Description
Specifications
| Size | 0.1 mg |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Specificity | This product detects an epitope within the C-terminal (CT) of human interferon regulatory factor 7 (IRF7), a 54kD transcriptional activator of type I interferons (IFNalpha/beta) in response to local and systemic viral infection. IRF7 is mostly expressed by plasmacytoid dendritic cells (pDC), which differentiate in response to IFNs and virus infection. This then stabilizes the IRF7 protein, in turn leading to increased IFN production. Multiple IRF7 transcript variants have been identified, although their individual functions have not yet been established. |
| Host Species | Rabbit |
| Protein Name / Synonyms | IRF7 |
| Preparation | Antisera to human IRF7 were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG prepared by affinity chromatography. |
| Concentration (lot specific) | IgG concentration 1.0mg/ml |
| Recommended Applications | Western Blotting |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
This product detects a band of approximately 51kDa in 293 whole cell lysate.
Storage/Stability
Store at +4 °C or at -20 °C if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 18 months after receipt.
Format
Supplied as:
Purified IgG - liquid
Formulation:
Phosphate buffered saline
Format Type:
Purified
Preparation
Antisera to human IRF7 were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG prepared by affinity chromatography.
Immunogen:
14 amino acid peptide sequence near the carboxy terminus of human IRF7.
Preservative:
| 0.02% | Sodium Azide |
Expiration:
12 months from the date of shipment when stored properly.