3607 Parkway Ln Ste 200 Norcross, Georgia 30092
www.RayBiotech.com | info@raybiotech.com
770-729-2992 | +1-888-494-8555
ISO 13485:2016 cGMP
Anti-IRF8 (Center) Antibody
Catalog #: 102-15168
Rabbit Anti-Human IRF8 (Center) Antibody, 400 ul
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | Q02556 |
| Gene Id | 3394 |
| Gene Symbols | IRF8 |
| Protein Name / Synonyms | IRF8 (Center) |
| Clonality | Polyclonal |
| Preparation | This IRF8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 241-269 amino acids from the Central region of human IRF8. |
| Concentration (lot specific) | 2.0 mg/ml |
| Recommended Applications | Western Blotting, FC |
| Research Area | Autophagy |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
Interferon consensus sequence-binding protein (ICSBP) is a transcription factor of the interferon (IFN) regulatory factor (IRF) family. Proteins of this family are composed of a conserved DNA-binding domain in the N-terminal region and a divergent C-terminal region that serves as the regulatory domain. The IRF family proteins bind to the IFN-stimulated response element (ISRE) and regulate expression of genes stimulated by type I IFNs, namely IFN-alpha and IFN-beta. IRF family proteins also control expression of IFN-alpha and IFN-beta-regulated genes that are induced by viral infection.
Specificity
Other Names
IRF8; ICSBP1; Interferon regulatory factor 8; Interferon consensus sequence-binding protein
NCBI Accession #
NP_002154.1
Format
Type
Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
48356
Recommended Dilutions
WB: 1:1000; FC: 1:10-50
 | Western blot analysis of anti-IRF8 Antibody (Center) (Cat# 102-15168) in Jurkat cell line lysates (35ug/lane). IRF8 (arrow) was detected using the purified Pab. |
 | IRF8 Antibody (Center) (Cat# 102-15168) flow cytometry analysis of Jurkat cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.