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Anti-IRGM (C-term) Antibody
Catalog #: 102-10957
Rabbit Anti-Human IRGM (C-term) Antibody, 400 ul
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | A1A4Y4 |
| Gene Id | 345611 |
| Gene Symbols | IRGM |
| Protein Name / Synonyms | IRGM (C-term) |
| Clonality | Polyclonal |
| Preparation | This IRGM antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 151-179 amino acids from the C-terminal region of human IRGM. |
| Concentration (lot specific) | 0.350 mg/ml |
| Recommended Applications | Western Blotting, IHC-P |
| Research Area | Inflammation, Autophagy |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
This gene encodes a member of the p47 immunity-related GTPase family. The encoded protein may play a role in the innate immune response by regulating autophagy formation in response to intracellular pathogens. Polymorphisms that affect the normal expression of this gene are associated with a susceptibility to Crohn's disease and tuberculosis.
Specificity
Other Names
IRGM; IFI1; IRGM1; LRG47; Immunity-related GTPase family M protein; Immunity-related GTPase family M protein 1; Interferon-inducible protein 1; LPS-stimulated RAW 264.7 macrophage protein 47 homolog
NCBI Accession #
NP_001139277.1
Other Accession #
NP_001139277.1
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
20142
Recommended Dilutions
WB: 1:1000; IHC: 1:10-50
 | IRGM Antibody (C-term) (Cat# 102-10957) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the IRGM antibody detected the IRGM protein (arrow). |
 | IRGM Antibody (C-term) (Cat# 102-10957)immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of IRGM Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.