Anti-ISL1 (Center) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human, Mouse
Host Species	Rabbit
Accession Number	P61371
Gene Id	3670
Gene Symbols	ISL1
Protein Name / Synonyms	ISL1 (Center)
Clonality	Polyclonal
Preparation	This ISL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 156-185 amino acids from the Central region of human ISL1.
Concentration (lot specific)	0.5 mg/ml
Recommended Applications	Western Blotting
Research Area	Angiogenesis, Cardiovascular Disease, Cancer, Inflammation
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

ISL1 is a member of the LIM/homeodomain family of transcription factors. The encoded protein binds to the enhancer region of the insulin gene, among others, and may play an important role in regulating insulin gene expression. The encoded protein is central to the development of pancreatic cell lineages and may also be required for motor neuron generation. Mutations in this gene have been associated with maturity-onset diabetes of the young.

Specificity

Predicted Reactivity

Rat, Zebrafish, Chicken

Other Names

ISL1; Insulin gene enhancer protein ISL-1

NCBI Accession #

NP_002193.2

Other Accession #

P61374; P61372; P53405; P50211; NP_002193.2

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

39036

Recommended Dilutions

WB: 1:1000

	ISL1 Antibody (Center) (Cat# 102-12956) western blot analysis in MDA-MB231 cell line lysates (35ug/lane).This demonstrates the ISL1 antibody detected the ISL1 protein (arrow).
	ISL1 Antibody (Center) (Cat# 102-12956) western blot analysis in mouse bladder tissue lysates (35ug/lane).This demonstrates the ISL1 antibody detected the ISL1 protein (arrow).

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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