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Anti-ITGB1BP3 (N-term) Antibody

Catalog #: 102-15141

Rabbit Anti-Human ITGB1BP3 (N-term) Antibody, 400 ul

Product Description

Specifications

Size400 µL
Estimated Lead Time1-2 weeks
SpeciesHuman
Host SpeciesRabbit
Accession Number
Q9NPI5
Gene Id
27231
Gene Symbols
NMRK2
Protein Name / Synonyms
ITGB1BP3 (N-term)
ClonalityPolyclonal
PreparationThis ITGB1BP3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 27-55 amino acids from the N-terminal region of human ITGB1BP3.
Concentration (lot specific)
2.0 mg/ml
Recommended ApplicationsWestern Blotting, IHC-P
Shipping TypeBlue ice
Storage-20°C

Description

Introduction

ITGB1BP3 catalyzes the phosphorylation of nicotinamide riboside (NR) and nicotinic acid riboside (NaR) to form nicotinamide mononucleotide (NMN) and nicotinic acid mononucleotide (NaMN). The protein reduces laminin matrix deposition and cell adhesion to laminin, but not to fibronectin. It is involved in the regulation of PXN at the protein level and of PXN tyrosine phosphorylation and may play a role in the regulation of terminal myogenesis.

Specificity

Predicted Reactivity
Mouse
Other Names
NMRK2; ITGB1BP3; NRK2; Nicotinamide riboside kinase 2; Integrin beta-1-binding protein 3; Muscle integrin-binding protein; Nicotinic acid riboside kinase 2; Ribosylnicotinamide kinase 2; Ribosylnicotinic acid kinase 2
NCBI Accession #
NP_733778.1
Other Accession #
Q9D7C9

Format

Type
Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
26046
Recommended Dilutions
WB: 1:1000; IHC: 1:10-50
Western blot analysis of ITGB1BP3 Antibody (N-term) (Cat# 102-15141) in K562 cell line lysates (35ug/lane). ITGB1BP3 (arrow) was detected using the purified Pab.
Formalin-fixed and paraffin-embedded human skeletal muscle tissue reacted with ITGB1BP3 antibody (N-term) (Cat# 102-15141), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.