Anti-ITGB2 Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Accession Number	P05107
Gene Id	3689
Gene Symbols	ITGB2
Protein Name / Synonyms	ITGB2
Clonality	Monoclonal
Preparation	Purified His-tagged ITGB2 protein(Fragment) was used to produced this monoclonal antibody.
Concentration (lot specific)	0.250 mg/ml
Recommended Applications	Western Blotting
Research Area	Angiogenesis, Inflammation
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

The product of this gene belongs to the integrin beta chain family of proteins. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. This gene encodes the integrin beta chain beta 2. A given chain may combine with multiple partners resulting in different integrins. For example, beta 2 combines with the alpha L chain to form the integrin LFA-1, and combines with the alpha M chain to form the integrin Mac-1. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling. Defects in this gene are the cause of leukocyte adhesion deficiency type I (LAD1). Two transcript variants encoding the same protein have been identified for this gene.

Specificity

Other Names

ITGB2; CD18; MFI7; Integrin beta-2; Cell surface adhesion glycoproteins LFA-1/CR3/p150,95 subunit beta; Complement receptor C3 subunit beta; CD_antigen=CD18; Flags: Precursor

NCBI Accession #

NP_000202.2;NP_001120963.1

Other Accession #

NP_000202.2

Format

Type

Mouse Monoclonal Antibody (Mab)

Calculated Molecular Weight (Da)

84782

Recommended Dilutions

WB: 1:100-500

ITGB2 Antibody(Cat# 102-10362) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the ITGB2 antibody detected the ITGB2 protein (arrow).

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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