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Anti-ITM2C (N-term) Antibody
Catalog #: 102-22626
Rabbit Anti-ITM2C (N-term) Antibody, 400 µl
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | Q9NQX7|Q4R540|NP_001012532.1|NP_001012534.1 |
| Gene Id | 81618 |
| Gene Symbols | ITM2C |
| Protein Name / Synonyms | Integral membrane protein 2C, Cerebral protein 14, Transmembrane protein BRI3, CT-BRI3, ITM2C, BRI3 |
| Clonality | Polyclonal |
| Clone | RB36714 |
| Isotype | Kappa, Rabbit |
| Recommended Applications | Western Blotting |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
Negative regulator of beta amyloid peptide production. May inhibit the processing of APP by blocking its access to alpha-and beta-secretase. Binding to the beta-secretase-cleaved APP C-terminal fragment is negligible, suggesting that ITM2C is a poor gamma-secretase cleavage inhibitor. May play a role in TNF-induced cell death and neuronal differentiation (By similarity).
Other Information
NCBI Accession #
NP_001012532.1;NP_001012534.1;NP_112188.1
Antigen Type
Synthetic Peptide
Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Calculated Molecular Weight (Da)
30224
Antigen Source
Human
Images
WB (1:1000)
ITM2C Antibody (N-term) (Cat. #102-22626) western blot analysis in A375 cell line lysates (35ug/lane).This demonstrates the ITM2C antibody detected the ITM2C protein (arrow).
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.