Rabbit Anti-Human JMJD2B (N-term) Antibody, 400 ul
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Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | O94953 |
| Gene Id | 23030 |
| Gene Symbols | KDM4B |
| Protein Name / Synonyms | JMJD2B (N-term) |
| Clonality | Polyclonal |
| Preparation | This JMJD2B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 428-459 amino acids from the N-terminal region of human JMJD2B. |
| Concentration (lot specific) | 0.470 mg/ml |
| Recommended Applications | Western Blotting |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
KDM4B is a histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a role in histone code. It does not demethylate histone H3 'Lys-4', H3 'Lys-27', H3 'Lys-36' nor H4 'Lys-20' and only able to demethylate trimethylated H3 'Lys-9', with a weaker activity than KDM4A, KDM4C and KDM4D. Demethylation of Lys residue generates formaldehyde and succinate.
Specificity
Other Names
KDM4B; JHDM3B; JMJD2B; KIAA0876; Lysine-specific demethylase 4B; JmjC domain-containing histone demethylation protein 3B; Jumonji domain-containing protein 2B
NCBI Accession #
NP_055830.1
Other Accession #
NP_055830
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
121897
Recommended Dilutions
WB: 1:1000
 | JMJD2B Antibody (N-term) (Cat# 102-11324) western blot analysis in A375 cell line lysates (35ug/lane).This demonstrates the JMJD2B antibody detected the JMJD2B protein (arrow). |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.
