3607 Parkway Ln Ste 200 Norcross, Georgia 30092
www.RayBiotech.com | info@raybiotech.com
770-729-2992 | +1-888-494-8555
ISO 13485:2016 cGMP
Anti-JMJD2C (C-term) Antibody
Catalog #: 102-11096
Rabbit Anti-Human JMJD2C (C-term) Antibody, 400 ul
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | Q9H3R0 |
| Gene Id | 23081 |
| Gene Symbols | KDM4C |
| Protein Name / Synonyms | JMJD2C (C-term) |
| Clonality | Polyclonal |
| Preparation | This JMJD2C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1023-1056 amino acids from the C-terminal region of human JMJD2C. |
| Concentration (lot specific) | 0.250 mg/ml |
| Recommended Applications | FC, Western Blotting |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
This gene is a member of the Jumonji domain 2 (JMJD2) family and encodes a protein with one JmjC domain, one JmjN domain, two PHD-type zinc fingers, and two Tudor domains. This nuclear protein functions as a trimethylation-specific demethylase, converting specific trimethylated histone residues to the dimethylated form. Chromosomal aberrations and increased transcriptional expression of this gene are associated with esophageal squamous cell carcinoma. Alternative splicing results in multiple transcript variants.
Specificity
Predicted Reactivity
Mouse
Other Names
KDM4C; GASC1; JHDM3C; JMJD2C; KIAA0780; Lysine-specific demethylase 4C; Gene amplified in squamous cell carcinoma 1 protein; JmjC domain-containing histone demethylation protein 3C; Jumonji domain-containing protein 2C
NCBI Accession #
NP_001140166.1;NP_001140167.1;NP_001140168.1;NP_055876.2
Other Accession #
Q8VCD7; NP_001140167.1; NP_001140166.1; NP_001140168.1
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
119982
Recommended Dilutions
WB: 1:1000; FC: 1:10-50
 | JMJD2C Antibody (C-term) (Cat# 102-11096) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the JMJD2C antibody detected the JMJD2C protein (arrow). |
 | JMJD2C Antibody (C-term) (Cat# 102-11096) flow cytometric analysis of K562 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.