Anti-KCNAB1 (N-term) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	Q14722
Gene Id	7881
Gene Symbols	KCNAB1
Protein Name / Synonyms	KCNAB1(N-term)
Clonality	Polyclonal
Preparation	This KCNAB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 15-44 amino acids from the N-terminal region of human KCNAB1.
Concentration (lot specific)	0.350 mg/ml
Recommended Applications	Western Blotting
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member includes three distinct isoforms which are encoded by three alternatively spliced transcript variants of this gene. These three isoforms are beta subunits, which form heteromultimeric complex with alpha subunits and modulate the activity of the pore-forming alpha subunits.

Specificity

Other Names

KCNAB1; KCNA1B; Voltage-gated potassium channel subunit beta-1; K(+) channel subunit beta-1; Kv-beta-1

NCBI Accession #

NP_003462.2;NP_751891.1;NP_751892.1

Other Accession #

NP_003462.2

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

46563

Recommended Dilutions

WB: 1:1000

Western blot analysis of lysate from human heart tissue lysate, using KCNAB1 Antibody (N-term)(Cat# 102-14269). 102-14269 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody. Lysate at 35ug per lane.

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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