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Anti-KCNJ11 (N-term) Antibody
Catalog #: 102-18192
Rabbit Anti-KCNJ11 (N-term) Antibody, 400 ul
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human, Mouse |
| Host Species | Rabbit |
| Accession Number | Q14654 |
| Gene Id | 3767 |
| Gene Symbols | KCNJ11 |
| Protein Name / Synonyms | KCNJ11 (N-term) |
| Clonality | Polyclonal |
| Preparation | This KCNJ11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human KCNJ11. |
| Concentration (lot specific) | 0.5 mg/ml |
| Recommended Applications | Western Blotting, FC |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
ATP-sensitive potassium (K(ATP)) channels are found in endocrine cells, neurons and both smooth and striated muscle, where they play an important role in controlling insulin secretion and vascular tone, and protect neurons under metabolic stress. Kir6.2 is a member of the inward rectifier potassium channel family, which is characterised by a greater tendency to allow potassium flow into the cell rather than out of it. It associates with the sulphonylurea receptor SUR1/ABCC8 to form a subfamily of K(ATP) channels that, when mutated or misregulated, are associated with forms of hyperinsulinemic hypoglycemia, neonatal diabetes, or pre-disposition to type 2 diabetes mellitus.
Specificity
Predicted Reactivity
Rabbit
Other Names
KCNJ11; ATP-sensitive inward rectifier potassium channel 11; IKATP; Inward rectifier K(+) channel Kir6.2; Potassium channel, inwardly rectifying subfamily J member 11
NCBI Accession #
NP_001159762.1
Other Accession #
O02822; Q61743
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
43541
Recommended Dilutions
WB: 1:1000; FC: 1:10-50
 | Western blot analysis of KCNJ11 Antibody (N-term) (Cat# 102-18192) in mouse stomach tissue lysates (35ug/lane). KCNJ11 (arrow) was detected using the purified Pab. |
 | KCNJ11 Antibody (N-term) (Cat# 102-18192) flow cytometry analysis of CEM cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.