Anti-KCNJ2 (C-term) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human, Mouse
Host Species	Rabbit
Accession Number	P63252
Gene Id	3759
Gene Symbols	KCNJ2
Protein Name / Synonyms	KCNJ2 (C-term)
Clonality	Polyclonal
Preparation	This KCNJ2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 401-427 amino acids from the C-terminal region of human KCNJ2.
Concentration (lot specific)	0.480 mg/ml
Recommended Applications	Western Blotting, IHC-P, FC
Research Area	Cardiovascular Disease
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. This protein is an integral membrane protein and inward-rectifier type potassium channel. This protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, probably participates in establishing action potential waveform and excitability of neuronal and muscle tissues. Mutations in this gene have been associated with Andersen syndrome, which is racterized by periodic paralysis, cardiac arrhythmias, and dysmorphic features.

Specificity

Predicted Reactivity

Rat, Bovine, Chicken, Pig, Rabbit

Other Names

KCNJ2; IRK1; Inward rectifier potassium channel 2; Cardiac inward rectifier potassium channel; Inward rectifier K(+) channel Kir2.1; Potassium channel, inwardly rectifying subfamily J member 2

NCBI Accession #

NP_000882.1

Other Accession #

Q64273; P49656; O18839; P35561; P52186; O19182

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

48288

Recommended Dilutions

WB: 1:1000; IHC: 1:50-100; FC: 1:10-50

	Western blot analysis of KCNJ2 Antibody (C-term) (Cat# 102-17019) in NCI-H460 cell line lysates (35ug/lane). KCNJ2 (arrow) was detected using the purified Pab.
	Western blot analysis of KCNJ2 Antibody (C-term) (Cat# 102-17019) in mouse lung tissue lysates (35ug/lane). KCNJ2 (arrow) was detected using the purified Pab.
	Formalin-fixed and paraffin-embedded human lung carcinoma reacted with KCNJ2 Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
	KCNJ2 Antibody (C-term) (Cat# 102-17019) flow cytometry analysis of NCI-H460 cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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