Anti-KDR (Y1175) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human, Mouse
Host Species	Rabbit
Accession Number	P35968
Gene Id	3791
Gene Symbols	KDR
Protein Name / Synonyms	KDR (Y1175)
Clonality	Polyclonal
Preparation	This KDR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1153-1182 amino acids from human KDR.
Concentration (lot specific)	0.5 mg/ml
Recommended Applications	Western Blotting, FC
Research Area	Angiogenesis, Cancer, Autophagy
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

KDR is a major growth factor for endothelial cells. This protein encodes one of the two receptors of the KDR. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc..

Specificity

Other Names

KDR; FLK1; VEGFR2; Vascular endothelial growth factor receptor 2; Fetal liver kinase 1; Kinase insert domain receptor; Protein-tyrosine kinase receptor flk-1; CD_antigen=CD309; Flags: Precursor

NCBI Accession #

NP_002244.1

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

151527

Recommended Dilutions

WB: 1:1000; FC: 1:10-50

	Western blot analysis of KDR (Y1175) Antibody (Cat# 102-17507) in mouse lung tissue lysates (35ug/lane). KDR (arrow) was detected using the purified Pab.
	KDR (Y1175) Antibody (Cat# 102-17507) flow cytometric analysis of MDA-MB435 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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