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Anti-KIST (KIS) (N-term) Antibody
Catalog #: 102-17783
Rabbit Anti-KIST (KIS) (N-term) Antibody, 400 ul
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human, Mouse |
| Host Species | Rabbit |
| Accession Number | Q8TAS1 |
| Gene Id | 127933 |
| Gene Symbols | UHMK1 |
| Protein Name / Synonyms | KIST (KIS) (N-term) |
| Clonality | Polyclonal |
| Preparation | This KIST (KIS) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human KIST (KIS). |
| Concentration (lot specific) | 2.000 mg/ml |
| Recommended Applications | Western Blotting, IHC-P |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
Upon serum stimulation, KIS, a member of the Ser/Thr protein kinase family, phosphorylates CDKN1B/p27Kip1, thus controlling CDKN1B subcellular location and cell cycle progression in G1 phase. This protein, which contains 1 RRM (RNA recognition motif)domain, may be involved in trafficking and/or processing of RNA. KIS is widely expressed, with highest levels in skeletal muscle, kidney, placenta and peripheral blood leukocytes.
Specificity
Predicted Reactivity
Rat
Other Names
UHMK1; KIS; KIST; Serine/threonine-protein kinase Kist; Kinase interacting with stathmin; U2AF homology motif kinase 1
NCBI Accession #
NP_001171692.1;NP_653225.2;NP_787062.1
Other Accession #
Q63285; P97343
Format
Type
Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
46546
Recommended Dilutions
WB: 1:1000; IHC: 1:50-100
 | Western blot analysis of anti-KIS Pab (Cat# 102-17783) in mouse heart tissue lysate. KIS (arrow) was detected using purified Pab. Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence. |
 | Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma. |
 | KIS Antibody (C6) (Cat# 102-17783) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the KIS antibody detected the KIS protein (arrow). |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.